Alzheimer’s disease is the neurodegenerative, chronic disorder that is linked to the progressive neuronal loss along with the cognitive decline that affects the elderly patients aged between 65 to 80 years.
The causes of Alzheimer’s disease are multi-factorial such as genetic origin along with unknown etiology.
AD patients suffer from cognitive impairment, speech difficulty along short or long-term memory loss. Psychosis, depression and aggressive behavior characterize Alzheimer’s disease.
Alzheimer’s disease is one of the types of dementia that results in havoc for a person’s memory along with his behavior and thoughts.
The symptoms of Alzheimer’s disease worsen slowly, and every case varies from the other. However, the results are typically the same. This condition makes your daily activities extremely difficult with time and cannot be managed by the patient or the caregiver.
Alzheimer’s disease is one of the most common forms of dementia, and around 60-80% of cases are diagnosed with dementia.
According to the findings of Alzheimer’s Society of Canada, there is a massive number of the public suffering from this disease:
- 45%- the people who are at risk of developing dementia and increase up to 45% primarily for smokers.
- 65%- the people who are diagnosed are especially women and aged around 65 years or above.
- 16,000- Canadians but aged under 65 and living with dementia.
- 25,000- Newly diagnosed cases of dementia.
- 56,000- Canadian patients who have dementia and annually treated in hospitals.
- 564,000- People living in Canada and currently have dementia.
- 937,000- Canadians who will end up living with dementia within the upcoming 15 years.
- Over 1 million Canadians who are indirectly or directly affected by dementia.
- $10.4 billion costs annually spend in Canada to take care of dementia patients.
There is a considerable number of people suffering from this tragic disease, due to which there is a drive to find new and effective medications to treat Alzheimer’s disease. One such natural alternatives includes the use of CBD oil.
How can CBD cure Alzheimer’s disease?
Alzheimer’s disease results in severe effects until the patients can no longer take care of themselves. Unfortunately, until this time there is no cure for this disastrous disease. However, CBD or cannabis oil can help in slowing down the progression of Alzheimer’s disease.
Mechanism action of CBD for curing the Alzheimer’s disease
The CB1 receptors are present in the hippocampus area which is involved in the memory and learning center whereas CB2 receptors are found in the specialized type of immune cells, i.e., microglia.
The hippocampus area is involved in Alzheimer’s disease which is vulnerable to the underlying causes linked with this disease. It contributes towards the problems associated with learning and memory issues related to Alzheimer’s disease.
It is also believed that microglia cells are also involved in the progression of this disease. Some studies, also conclude that patients with Alzheimer’s disease have increased the number of CB2 receptors present in the brain.
The scientific research indicates that the endocannabinoid system plays an essential role by evoking the adaptive response which counteracts the inflammatory and neurochemical consequences of the Beta-Amyloid proteins which are the hallmark and the underlying cause of the Alzheimer’s disease.
CBD or Cannabidiol is available in multiple forms such as tinctures, edibles, oils, and many others. The CBD oil, in particular, is gaining popularity due to its medical effects. CBD can cure Alzheimer’s disease by the following results:
- Cannabis oil has an anti-inflammatory effect
Neurodegenerative conditions, for example, Multiple Sclerosis, Parkinson’s and Alzheimer’s disease, often involve the inflamed neural tissues. During the initial stages of inflammation, it is thought that the inflammatory phase serves as a defense mechanism.
However, in later stages, it leads to the uncontrolled chain reactions resulting in chronic neuronal inflammation along with deterioration.
If you consume Cannabis oil as a natural anti-inflammatory alternative, it helps in slowing down the progression of Alzheimer’s disease.
- Cannabis oil serves as an anti-oxidant agent
The key components involved in Alzheimer’s disease are oxidative stress and reactive oxygen which are tied to the immune inflammation.
During inflammation, oxidative stress is generated which results in the reduction of antioxidant function of the cells.
The oxidative stress further leads to the production of free radicals and chemical reactions with the fatty acids and proteins present within the cell membrane.
When Amyloid Beta-protein is present, it results in the elevation of a reactive type of oxygen species in the adjoining cells through the exchange process with the membranes.
The overall oxidative stress process leads to the neuronal loss along with the loss of synapses within the brain which leads to memory loss and other neurological symptoms.
So, during this condition, an antioxidant, i.e., CBD oil will help in slowing down Alzheimer’s disease.
- Cannabis oil serves as a neurogenesis stimulant
CBD oil is gaining attention for serving as a neurogenesis stimulant, i.e., it aids in the formation of the neural tissues by the neurogenesis process.
During the Alzheimer’s disease, the neural tissues rapidly deteriorate resulting in debilitating neurological impacts such as cognitive loss, memory loss along with severe changes in behavior or personality.
In fact, during this condition people who were seen as kind, loving and gentle can turn in to selfish and mean individuals due to which their loved ones have difficulty in understanding them.
CBD oil is believed to help in the formation of neurons and aids in slowing down the progression of Alzheimer’s disease.
Research studies and educational resources
According to some research, the role of the endocannabinoid system is a potential target for the treatment of Alzheimer’s disease.
Some studies have shown that the components of the Cannabis, i.e., THC aids in removing the Alzheimer’s hallmark Amyloid Beta-protein clumps present in the nerve cells which are grown in the lab.
According to another study, a combination of CBD and THC was given to the mice that showed the Alzheimer’s disease symptoms were improved with it.
The learning capability was enhanced, and the amyloid clumps were less evident in their bodies.
Other researchers believed that targeting CB2 receptors helped in controlling the activity of the microglia cells, preventing the harmful overactivation of the immune system within the brain.
However, still, there are no studies carried out on people to find out the effects of the CBD oil or its components on the treatment of the underlying causes of Alzheimer’s disease.
However, laboratory studies showed some promising results, but there need further studies and research to find out the beneficial effects of CBD oil in people with Alzheimer’s disease.
You must notice that many of these studies show the use of a specific component of Cannabis in isolated form.
Even if some studies show that the single element has helped in reducing the risk of dementia, it does not include that the entire cannabis will result in the same effects.
CBD strains have different levels of CBD and THC, so you need to aware of the type of Cannabis used and its consequences.
According to a research carried out by Tim Karl and Carl Group, to identify the properties of CBD, i.e., neuroprotective, anti-oxidant and anti-inflammatory effects in vitro. These features were concluded to benefit and cure Alzheimer’s disease.
The in vivo studies show that CBD oil aids in reducing the reactive gliosis and the neuroinflammatory response which is associated with Alzheimer’s disease.
The findings also conclude that CBD promotes the development and growth of neurons which in turn reduces the deteriorative effects related to the disease.
In preclinical animal studies, the dosage of CBD Oil for three weeks aids in reversing cognitive effects and prevents the development of memory deficit effects linked with Alzheimer’s disease.
Some studies indicate that the use of CBD along with THC- a psychoactive compound leads to even more significant therapeutic effects for the treatment of Alzheimer’s disease.
According to a study, a drug containing a combination of CBD and THC leads to the reduction of gliosis along with the decreased buildup of alpha-beta and tau.
Additionally, the researchers also discovered, a combination of THC and CBD treatment results in enhanced anti-dementia effects and allows you to avoid the euphoric impact which might occur if THC is used alone.
Which cannabis strains help with Alzheimer’s?
The top 10 cannabis strains which help in treating Alzheimer’s disease include the following:
- Electric Kool-Aid (Hybrid)
- Dutch Dragon (Sativa)
- Acapulco Gold (Sativa)
- Lavender Haze (Sativa)
- Green Crack (Sativa)
- Bio Jesus (Hybrid)
- LSD (Hybrid)
- White Russian (Hybrid)
- The OX (Indica)
- Blissful Wizard (Hybrid)
CBD oil dosage for Alzheimer’s treatment
For CBD tinctures, you need to begin with a small dosage i.e.
CBD: consume 5-10 drops thrice daily
THC: drink three drops twice or thrice daily. You can increase the dose by one drop after every 48-72 hours for each dosing. It allows you to avoid being high.
Tinctures (1:10) are around 1000 mg of the cannabinoid extract in every 10 ml of MCT, i.e., 500 or more drops in each bottle and each drop weighs approximately 2 mg.
For the treatment of movement problems associated with Alzheimer’s disease, consume 3-5 mg of CBD oil for each pound of body weight on daily use. If your body weight is around 150 lbs, then you need to drink 450-750 mg of CBD oil daily.
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Which CBD oil is best for Alzheimer’s disease?
The best CBD oils for Alzheimer’s disease include the following:
It is the most beneficial and potent hemp extract offered by this brand. The CBD oils comprise of the naturally occurring terpenes, cannabidiol along other cannabinoids.
These oils are entirely organic, quality tested by the third parties for pesticide-free oils.
The company provides the customers with CBD oils which are the third-party tested for cannabinoid profiling, microbiological screening, pesticide testing, terpene analysis, and residual solvent testing. It is 100% safe, efficient and Certified Pure.
Elixinol is a Colorado-based company which derives the best quality CBD products from the best hemp produced in the world. Elixinol offers the high-quality CBD Oil to the customers.
They are 100% organic and derived from the industrial hemp. The CBD oil manufactured by Elixinol are tested for their potency, quality, and purity.
Koi CBD is the California-based company that manufactures the CBD or cannabidiol derived from the hemp plant.
Koi uses the 99% pure form of Cannabidiol extracts through the pharma-grade methods in a cGMP facility which is certified.
The process allows the company to achieve the finest and consistent way of hemp extracts CBD which is available in the market for the consumers. Each CBD product by the koi company is fully traced for its quality from start to the end.
Koi CBD is considered legal in all the 50 states of the US and comprises the 0% THC so that the consumers can enjoy the CBD products which do not result in high feelings.
Alzheimer’s is a destructing disease for an individual to survive along with family and friends.
So, when we need to consider CBD oil and its medical effects regarding this tragic disease, it is worth to dive in and research about this natural alternative and its beneficial effects.
CBD Oil serves in reducing the progression of Alzheimer’s disease. However, consult your doctor or physician before you begin to consume the CBD oil.