Businessman, students, teachers and many other demanding lifestyles require a quick boost of their energy and motivation.

These days it is effortless to increase your motivation and energy levels. It is common to buy supplements and consume them for overcoming procrastination or depression along with increased motivation level.

Every individual is accustomed to use stimulants such as caffeine or have energy drinks to help improve the mental drive.

However, day by day nootropics are in the limelight, and many individuals prefer to eat these drugs as they are an efficient and safe way to benefit you an extra jump in each step.

Neuroscientists have designed the nootropic supplements to improve the energy and cognitive abilities.

However, these compounds also provide multiple benefits along with this function.

These advantages include increased mental vitality, overall energy, increase the motivation and helps in improving mood.

Nootropics stimulate the processing and release of brain chemicals which results in energy for both body and mind.

It increases the physical stamina along with enhancement of mental capacity which allows you to play, work and think better.

How do Nootropics work?

Nootropics enter the Central Nervous System and can cross the blood-brain barrier. After entering they modulate the levels and activity of different neurotransmitters.

These neurochemicals, for example, Norepinephrine, Dopamine and Serotonin help in the mediation of cognitive processes such as learning, decision making, memory formation and logical reasoning and so on.

Nootropics enhance the energy supply to the brain and mental performance which increases the blood flow towards the brain.

The improvement in cerebral circulation is due to the oxygen uptake and increase in glucose metabolism within the neurons.

Nootropics keep you alert and awake and reduce your symptoms of fatigue and drowsiness. Nootropics may also produce anti-anxiety effects which increase the drive and productivity.

Best Nootropics for energy & motivation

Following are the best nootropics for energy which help to boost productivity along with motivation.

  • Phenylpiracetam For Mental Energy

    Also known as Phenotropilor Carphedon. It belongs to the Racetam drug. It can pass the blood-brain barrier as it contains the additional Phenyl group in the original Piracetam family.

    The addition of Phenyl group makes this supplement more potent and energizing when compared to the Piracetam.

    It is 60-65 times more potent when compared to the original supplement.

    It helps in enhancing the mental energy along with stimulation of CNS. Phenylpiracetam is useful for enhancement of memory, energy and physical performance.

    It does not lead to any crash and spike but results in clean stimulation. Phenylpiracetam acts on dopamine receptors which result in boosting the mood.

    It results in less anxiety and happier effects along with motivation.

    Phenylpiracetam leads an individual to purpose-driven and highly focused state. Athletes also consume this supplement to enhance their recovery, stamina along with endurance abilities.

    Phenylpiracetam stacks well with CDP Choline, Alpha GPC, Centrophenoxine, Piracetam and Sulbutiamine. The typical dose is around 100-200 mg, and half-life is 3-5 hours.

  • Adrafinil/ Modafinil

    They are closely related drugs and provide numerous benefits such as improving attention and wakefulness.

    When Adrafinil has processed, it converts into Modafinil while in the liver.Modafinil is supplied by the name of Modiodal or Provigil.

    It is a type of smart drug which enhances the motivation and one of the best nootropics for energy levels.

    When Adderall is compared to Modafinil i.e. (Dextroamphetamine and Amphetamine), then Modafinil is preferred because it provides clean energy and motivation for long periods and also results in minimum side effects.

    While Adderall, on the other hand, results in addiction and dependency issues.

    Modafinil is a type of schedule 4 controlled substance which is only available when prescribed while Adrafinil is readily accessible.

    They were previously developed to treat individuals with sleeping disorders such as narcolepsy, for Attention Deficit Disorder, sleep apnea, and excessive fatigue.

    Modafinil is used to promote energy, focus, learning, motivation, memory and physical performance.

    Modafinil stacks well with Aniracetam, Acetyl-L-Carnitine, Noopept, and Phenylpiracetam. It has a half-life of 15 hours, and its typical dose is around 50-200 mg.

    Modafinil acts on multiple neurotransmitters such as Orexin or Hypocretin system, histamine, norepinephrine, dopamine, and serotonin both as a nootropic and eugeroic.

    Modafinil helps to reduce the strain when on excessive mental exertion and contributes to increasing the perceptual awareness.

    Modafinil allows concentrating on your work without any distractions and helping you achieve your goals.

    These two nootropics have minimum side effects i.e. they do not lead to anxiety, jitteriness or any types of symptoms associated with withdrawal crash.

    It has non-severe and minor side effects which include nausea, headache, indigestion, insomnia, dizziness, diarrhea, inflammation of the nose and dry mouth.

    Adrafinil is known as Olmifon and CRL-40028. It is suitable for enhancement of focus, energy, learning, memory, physical performance and motivation.

    It stacks well with Phenylpiracetam, Noopept, and Piracetam. Its half-life is around 1 hour, and the typical dose is 150-300 mg.

    It is a synthetic type of nootropic supplement which acts as a stimulant. It helps to increase wakefulness and energy along with it prevents fatigue.

    It acts on the adrenergic system which produces the adrenaline. The adrenaline helps in increasing alertness and boosts energy.

    The most common side effects of Adrafinil include dizziness, stomach upset, nausea and headaches.

  • Noopept

    In 1990s Noopept was developed as a Nootropic supplement in Russia. Noopept is the strongest nootropic which is readily available on the market.

    It has a psychostimulatory effect along with a boost; it has a different mechanism of action than other Racetams although it belongs to the same family.

    It increases the Brain-Derived Neurotrophic factor along with Nerve Growth Factor and is 1000 times more potent than Piracetam.

    Noopept acts on Glutamate and Acetylcholine receptors which result in increased motivation and energy levels.

    Noopeptenhances the activity of beta and alpha waves which results in improved socializing, writing, reading and thinking skills.

    The most significant benefit of Noopept is that it enhances the attention and concentration by improving the memory capacity.

    Noopept provides you with focus, cognition, exceptional clarity and helps in reducing brain fog.

    Noopept stacks well with Alpha GPC, CDP Choline, Aniracetam, Piracetam, Centrophenoxine and Sulbutiamine.

    The added advantage of this supplement is that it can be consumed on a daily basis when compared to other drugs.It is half life around 30-60 minutes, and the typical dose is 10-30 mg.

  • Bacopa

    It is a type of natural supplement extracted from plants found especially in India. This supplement is the preferred option if you want to opt for a herbal supplement.

    Its mode of action depends on amplification of neurotransmitters within the brain by enhancing the electrical conductivity of neurons. It results in a natural boost for energy and motivation levels.

    Bacopa increases the activity of Serotonin and Acetylcholine which results in lower anxiety levels and enhanced brainpower.

  • Aniracetam

    Aniracetam is one of the most efficient drugs which increase the energy, ambition, motivation, and determination. It creates a state of focused relaxation which leads to motivation.

    It increases the concentrations of Dopamine and Serotonin which enhance the energy and results in relaxation along with real emotions to maintain the motivation and energy levels.

    Aniracetam also acts as an anti-depressant and comprises of anxiolytic properties. It increases the blood flow to the brain’s cortex which results in improved thinking capability.

    You can also add Choline in your Aniracetam stack which helps to increase motivation and energy.

    Citicoline or Alpha GPC supplements also assist in eliminating the headaches which occur due to Choline deficiency.

  • Piracetam

    It is a perfect motivation and energy enhancer. When compared to Aniracetam it is less potent and more popular in Racetam category. Piracetam acts as serotonin and dopamine reuptake inhibitor.

    Piracetam is beneficial for treating the cognitive impairment in older individuals.

    Piracetam enhances the cellular membrane fluidity within the brain. Its prime function is a cognitive enhancement.

    It has anxiolytic properties and helps in improving the creativity level. It has a benefit of reducing the anxiety levels along with a focus on tasks.

  • Pramiracetam

    It is similar to Aniracetam and Piracetam, but it is more potent when compared to these two i.e. around 15-30 times. Pramiracetam influences the acetylcholine and glutamate receptors.

    It improves the efficiency and reuptake of these channels. Pramiracetam enhances focus, increases motivation and memory, improves learning and logical thinking capability.

    Pramiracetam enhances motivation and energy by increasing the levels of nitric oxide synthase within the cerebral cortex.

    Pramiracetam is a synthetic supplement which is great for motivation and energy when added to the nootropic stack.

    Pramiracetam may also affect the readings of electroencephalography (EEG) which measures the brain’s electrical activity.

    Pramiracetam is fat-soluble, and its recommended dosage is around 200-400mgs.

  • Armodafinil

    It is a type of wakefulness-promoting drug which helps to treat excessive sleep disorder and increases the motivation along with energy in individuals who consume it.

    It is sold by the name of Nuvigil. It has the same effects as Adrafinil and Modafinil, but the difference lies in its potency.

    It is similar to Modafinil, but there is a slight difference in their components.

    Modafinil contains the r-enantiomer along with s-enantiomer while on the other hand, Armodafinil contains the r-enantiomer.

    It is advised to consume the half amount of Armodafinil when compared to the Modafinil dosage.

  • L-Tyrosine

    It is an amino acid which helps to improve memory and mood, enhances the cognitive abilities, reduces the stress effects and increases focus.

    It supports mental performance and promotes the high brain chemistry.

    The brain chemistry then results in the production of epinephrine, norepinephrine, and Dopamine which are also termed as Catecholamines.

    These neurotransmitters have positive effects on mood, motivation, energy levels and cognitive function. It is available in the market as N-Acetyl L-Tyrosine (NALT) which is an added bioavailable form.

    It has multiple benefits such as improves learning, mood and focus abilities, promotes motivation and energy.

    It is a type of natural stimulant which stacks well with Aniracetam, CPD Choline, Noopept, Phenylpiracetam, and Sulbutiamine.

    The typical dose of this supplement is around 500-1000mg if taken in L-Tyrosine form and 300 mg if taken as NALT form.

    Following are the side effects of L-Tyrosine such as a migraine, headaches, indigestion, gastrointestinal upset, and stomach trouble.

    L-tyrosine is contraindicated in patients with Thyroid disease, Melanoma, Graves’ disease, patients who are on high blood pressure medicines. It is not proven to be safe for lactating or pregnant ladies.

  • Oxiracetam

    It is known as Neuromet, Neuractiv, and Hydroxypiracetam. It is highly effective, potent and safe drug. Oxiracetam is the most popular and best nootropic supplement.

    It is an actual brain booster which enhances the cognitive process. It is a mild stimulant which restores and improves the mental and physical energy. It improves the memory, focus, learning and energy levels.

    Oxiracetam stacks well with Alpha GPC. It has a typical dose of 800-1500 mg with a half-life of 8 hours.

    Oxiracetam affects glutamatergic and cholinergic systems which modulate the release of glutamate and acetylcholine neurotransmitters.

    Both have the properties to enhance learning, memory and cognitive functions. Oxiracetam is long-lasting and more efficient.

    It helps in enhancement of neuronal communication. It is a mild type of Central Nervous system stimulant. Oxiracetam is a form of the awater-soluble compound which can cross the blood-brain barrier.

    Oxiracetam is an amazing supplement as it lacks the severe side effects. It is non-toxic and safe drug even if taken in high doses.

    The most common adverse effect includes a headache, gastric distress, and temporary indigestion.

    Oxiracetam may also interfere with sleeping patterns. Rare side effects such as nervousness and insomnia may also occur.

  • Rhodiola Rosea

    It is a type of natural nootropic which allows you to give your best at mental and physical level.

    It helps to boost your cognitive abilities, fights fatigue and provides protection to your body and brain against adverse effects of tension and anxiety.

    Rhodiola Rosea is also known as Rose root or Golden root. It is beneficial to enhance your mood and energy levels, improves your memory and reduces anxiety. The typical dose of this drug is around 100-500 mg.

    It affects the modulation of molecular networks and signaling pathways via phytochemical components which act as Monoamine oxidase inhibitors.

    It slows down the breakdown of neurotransmitters which are involved in mood stabilization such as Dopamine and Serotonin.

    The common adverse effects include anxiety, dizziness, insomnia, agitation, restlessness, nausea and libido.

  • Acetyl-L-Carnitine

    It is a multi-purpose supplement which benefits both body and brain. It has neuroprotective and antioxidant properties. It reduces the aging effects and enhances the energy levels.

    Acetyl-L-Carnitine is also known as Acetylcarnitine or ALCAR. It is a cholinergic type of supplement.

    It stacks well with Piracetam, Pramiracetam, Noopept, and Aniracetam. It works well for boosting energy and motivation levels and improves the learning and memory skills.

    Its half-life is around 1-4 hours, and typical dosage ranges from 500 mg. ALCAR is well tolerated, safe and affordable. It is readily available in the market without any prescription.

    It has multiple benefits which include cognitive enhancement, effective neuroprotectant, provides physical health benefits and acts a potential treatment agent for Age-related disorders.

    It works by enhancing the production of important neurotransmitters such as Acetylcholine and improves the brain metabolism due to its antioxidant properties.

    ALCAR is a powerful neuroprotective supplement as it strengthens the myelin sheath.

    The two most common side effects include a headache and individuals have reported issues such as nausea when ALCAR is taken with food.

Other Nootropics

There are many other types of additional motivation and energy boosters which belong to the Nootropics family.

L-Theanine, caffeine, Sulbutiamine, the acrine and other supplements also have a noticeable effect on energy and motivation levels.

All these supplements help you to recharge your motivation and energy.


Despite what people say you can find energy and motivation in pill form. The nootropic supplements enable you to achieve goals in life and allow you to be motivated for your task.

If you wish to work and earn for yourself but lack the drive or energy to achieve it, then nootropics are the ultimate option.

These supplements are well known and completely tested with excellent reputations as body and brain boosters especially Noopept, Adrafinil, and Phenylpiracetam.

All the supplements mentioned above are safe, affordable and readily available without any serious side effects if taken in recommended dosage.

It is hard to find the best nootropic according to your body as every individual reacts differently to these supplements.

However, you can try any of the above-mentioned supplements and find a solution for your demanding lifestyle.

Asad Khan is an independent health journalist who specializes in food policy and global health. He is a senior fellow for investigative health journalism at the Bonn-Rhein-Sieg University of Applied Sciences, Germany.