HomeNootropicsWhat Are The Most Effective Noopept Stacks And Dosages?

What Are The Most Effective Noopept Stacks And Dosages?

Are you searching about the best Noopept stacks? Don’t know much about them?

Then you are at the right place. We will tell you each and everything about Noopept.

The most efficient Noopept stacks, ways to consume them, their dosages and effects.

What is Noopept?

Noopept is a type of peptide drug common in Russia as a nootropic. It is also called Neuropeptide, GVS-111 or N-phenyl acetyl-L-polyglycine ethyl ester. Noopept is a psycho-stimulant which belongs to the Racetam category.

Noopept supplements referred to as smart drugs which help in enhancing the cognitive abilities.

It helps in improving the memory, skills, perceptual awareness and concentration. Noopept stimulates the receptors of the brain which helps in improving the levels of neural activity and cognition.

However, this will only provide you with half results. However, a stack of Noopept which combines natural Noopept supplements along with smart drugs increases the brain power along with strengthening the benefits of the supplements.

Noopept is neuroprotective and prevents the brain from cellular damage. Noopept also helps in treating the degenerative disorders such as Parkinson’s, Alzheimer’s, schizophrenia or dementia.

How do Noopept supplements work?

The Noopept drug interacts with the neurotransmitters in the brain and results in increased activity of alpha waves throughout the brain region. The activity results in improved cognitive enhancement.

Noopept has an antioxidative action that prevents neurons from apoptosis. It inhibits the glutamate neurotoxicity.

It increases the neuronal plasticity with increased expression of endogenous nootropics which include pro-glycine, phenylacetic acid and cyclo-pro-glycine and others.

The chemical formula of Noopept is based on a type of brain chemical i.e. Cycloprolylglycine (CPG).

It is claimed by scientists that Noopept converts into CPG which has anti-oxidant and anti-anxiety effects.

It boosts the energy and mental alertness. Promotes the health of the brain and increases the BDNF (brain-derived neurotrophic factor) and NGF (nerve growth factor). It supports focus, mood, and memory.

Noopept dosages

Noopept is easily available in powder, capsule, tablet or pill form. It is recommended not to increase the dosage from 10-40 milligrams each day.

Avoid increasing the dose beyond 40 mg. Noopept has a very short half-life i.e. 30-60 minutes, so it is better to ingest multiple small doses rather than a large dose.

Noopept, when taken sublingually in powder form, provides rapid effects that are within 15-20 minutes.

It is advised according to the dosing label that Noopept should be consumed for 1.5-3 weeks and then restart with another cycle after taking a month break.

Avoid taking Noopept in the evening as it interferes with sleep patterns.

The various levels of Noopept dosages are following:

  • Threshold=7mg
  • Low=7 mg – 10 mg
  • Moderate=10 mg – 20 mg
  • High=20 mg – 35 mg

How to measure a Noopept does?

You can measure small Noopept dose by using a weighing scale or by using a micro milligram scoop. Both the measuring methods are readily available in the market. [1]

Which form of Noopept is better capsule or powder form?

The choice between both of them depends on your lifestyle. Capsules are easier to ingest and are available in pre-stacked forms. However, they are expensive, and you cannot control the dosage.

So make your decision what results you need by consumption of Noopept and then make the purchases. If you are at the beginner level and budget conscious, then prefer powder form.

What is stacking and why to stack different Nootropics?

  • The practice to stack supplements started from athletes who are seeking to achieve extra benefits by the synergistic effects of different compounds.
  • Stacking is defined as the practice of consuming 2 or more supplements in combined form to achieve the additional benefits or specific effects.
    It is a common practice in the world of cognitive enhancers and nootropics.
  • You can feel the difference by consuming a combination of different compounds instead of using one independently.
  • You must be wondering how to use the Noopept stacks and what to use it?
  • If you are using Noopept for the first time, then don’t consume it in stacks form instead start it independently.
    Noopept is thousand times stronger than Piracetam so one should start choline or Piracetam if you are at the beginner level.

Potential Noopept stacks

1. Noopept with Alpha GPC and Piracetam

Piracetam helps by enhancing the effects of Noopept while Alpha GPC improves the effects of Piracetam and helps in elimination of headaches.

Piracetam works on Acetylcholine neurotransmitters while Noopept operates on the Glutamate neurotransmitter.

The combination of these compounds improves the memory formation, cognitive ability, manipulation of concepts and computations.

Take it once or twice daily:

  • 2g of Piracetam
  • 10mg of Noopept
  • 300mg of Alpha GPC

2. Noopept stacks with Choline supplement along with Huperzine

Huperzine A is a type of acetylcholinesterase inhibitor which enhances the activity of Noopept on acetylcholine.

The herbal supplement Huperzine A prevents the breakdown of acetylcholine which is the extracellular form.

It allows the acetylcholine to stay active within the synaptic cleft for long periods.

It results in cholinergic stimulation and enhances the reuptake of presynaptic acetylcholine which helps in effective communication of brain.

Do not take larger doses of Huperzine A and greater than 50 mcg because it is a powerful Cholinesterase Inhibitor.

3. Add Aniracetam, Sulbutiamine and CDP Choline to Noopept

Which helps in enhancing the effects and helps in mood elevation. Noopept provides anti-anxiety benefits by stimulating Glutamate which breaks down to form GABA.

You can increase the effects of Noopept by adding Aniracetam, sulbutiamine and CDP Choline.

The stacks help in boosting the mood provides cognitive benefits and relaxed stimulation along with euphoria feeling.

You can also use this stack as a pre-workout combo with the addition of L-Theanine or caffeine.

The Sulbutiamine and Noopept stacks are recommended for people want to prevent anxiety and need a powerful brain boost.

In this combination, Sulbutiamine provides the anxiolytic effect by acting on the Dopaminergic system.

Must Read:  The Best Nootropics for Motivation and Euphoria

However, if you are at the beginner level then use Aniracetam or Pramiracetam with Noopept.

Take it once or twice daily:

  • 1g of Aniracetam
  • 300mg of Alpha GPC
  • 10mg of Noopept
  • 300mg of Sulbutiamine

4. Noopept and Choline Bitartrate stack

It has a synergistic relationship. Noopept allows the brain to be more responsive for choline which results in improved memory.

TheNoopept choline stack helps in improvement of memory along with cognitive performance.

The addition of Choline in Nootropic stacks helps in maintaining the cell membrane and acts as a necessary precursor for Acetylcholine which helps in memory function.

Choline helps in improving the mood instability, concentration, and memory deficits.

Choline also helps to mitigate the headache side-effect which usually occurs due to the Noopept use.

Dosage: 250-1000 mg each day.

Choline has different types, and you need to choose between them, for example, Citicoline, and Alpha GPC can cross the Blood-brain barrier and is required in large amounts to fulfil the purpose.

Other types of Choline supplements are necessary for small doses such as Phosphatidyl Choline powder and Choline Bitartrate.

For consumption of Noopept Alpha GPC stack, you need to mix 20* extra amount of Alpha GPC than Noopept.

Example: 400 mg of Alpha GPC is mixed with 20 mg of Noopept however for citicoline the dosage ratio is 1:30.

5. Noopept and Phenibut stack

It helps in improvement of mood, alertness, and sociability. The stack results in euphoria feelings.

The Noopept acts as a stimulant and boosts alertness, cognition, and memory. However, Phenibut is a socializing, anti-anxiety and calming substance.

6. Noopept and L-Theanine stack

It allows you to be focused and relaxed. L-Theanine is a natural variant derived from green tea.

It is a type of a calming amino acid which creates a relaxed and calm mood without any drowsiness. L-Theanine enhances the effects of Noopept’s cognitive ability.

7. Noopept and alcohol stack

Noopept improves the cerebral blood flow and helps in recovering brain from damage that may occur due to toxins and stress.

It is claimed by individuals that Noopept lessens the hangover effects created by alcohol while some people report that it creates a sense of clear-headedness and clarity.

How to design your Noopept stacks?

The idea is to stack Noopept by combining the nootropic supplements and getting the right effects according to your needs.

Think about your goals and what do you want to accomplish by consumption of these cognitive enhancers and brain-boosting drugs.

You have two options:

  • Add Racetam such as Aniracetam, Piracetam, Pramiracetam, and others or you can add herbal nootropics and Ampakines.
  • Add unrelated ingredients ex. Preformulated nootropic supplements such as Mind Lab Pro to enjoy multiple benefits of Noopept and other ingredients.
    However, analyze the mechanism of action of these supplements as the combination may result in an allergic reaction or cause adverse effects.

Take it once or twice daily:

  • 10mg of Noopept
  • Two capsules of Mind Lab Pro

You can only achieve the best combination by trial basis, and experimentation helps in creating the perfect stack with right effects.

Cycle Noopept stacks or not?

Many individuals wonder whether to cycle Noopept stacks or not? You cannot use Noopept continuously as it may stop providing effects because it has mid-level of tolerance buildup.

So it is better to cycle Noopept because the body gets used to its consumption.

It is advised to stack for around one week then take a break of 5-6 days and come back on for 3-4 days.

Do not maintain the same cycle keep changing things so that your body does not adjust to its use.

How to consume Noopept

The best way to consume Noopept is by placing it under the tongue. When you place the Noopept sublingually, it quickly works into the bloodstream. However, it varies from individual to individual.

Some individuals take Noopept in capsule form while others try to dissolve it in water although it is not that soluble. Some also eat it in powder form and then drink water on it to mask its taste.

Noopept Pros and Cons

  • ProsThe drug promotes memory and cognitive function.
    Provides anxiolytic effect and acts as a mild stimulant.
    It increases the BDNF mRNA and NGF concentrations.
    It provides the neuroprotective effect.
    The recommended dosage is around 15-30 mg.
  • ConsIt has a drawback of insufficient human research.
    Results in a headache, irritability, loss of appetite and excessive dose may lead to depression and brain fog.

Things to remember before you are stacking the supplements:

  • Mix in small doses of nootropics when you are at the beginner level. Assess and evaluate yourself that which stack works well for you.
  • Avoid consuming stacks at higher dosages because it may result in severe side effects.
  • Consult your doctor for your medical condition if you want to start nootropic stacks.
  • It is not suggested to consume nootropic agents while you are breastfeeding or pregnant as the effects are not yet studied on expecting and lactating mothers.
  • Stop using the stacks as soon as you experience some side effects.


You need to carefully select Nootropics as all of them have a particular purpose. When combined with stack forms they synergize with each other and provide you with best results.

Noopept is an amazing Nootropic either used alone or in combination with other compounds. Noopept helps in improvement of memory, learning, and brain functions and creates a sense of focus and clarity.

We would highly recommend you to try any of these stacks and if you find your body to react positively towards it then continue with that combination.

However, be aware not to overdose the stacks and use it according to the recommended dosage. You can easily use it because of its low dose and economical price.

Asad Khan
Asad Khan is an independent health journalist who specializes in food policy and global health. He is a senior fellow for investigative health journalism at the Bonn-Rhein-Sieg University of Applied Sciences, Germany.

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