Physicians along with the medical practitioners are still wondering to understand the fact that what is nausea and how it happens.

Many tinctures, breathing techniques, and pharmaceuticals have been questioned about their ability to eliminate the symptoms of vomiting and nausea.

Many medical treatment options along with other remedies are available which aids in reducing the specific cause leading to nausea.

For example, people who suffer from motion sickness are advised with Dimenhydrinate or Dramamine.

These medical treatment options are useful, but we need to find out a natural remedy which might aid in treating the biological cause associated with vomiting and nausea.

Scientists are trying to research this topic and have led to the accumulation of several theories which might help in treating nausea and vomiting.

They have managed to study about cannabinoids and their numerous beneficial effects on the human body, one of which includes the treatment of nausea and vomiting.

Cannabis serves as a mystery for many individuals up till now. There have been numerous research and studies regarding this ancient herb, but still, the facts about cannabis capabilities are not entirely known.

Majority of the Cannabis studies revolve around THC which is a type of psychoactive compound making you feel high or stoned. However, CBD, on the other hand, is well-known for its likely effects on the human body.

THC along with other cannabinoids interact with the CB receptor sites which includes CB1 and CB2 receptors.

However, CBD produces the medicinal qualities by activating an Endogenous Cannabinoid system due to the production of an enzyme termed as Anandamide.

CBD oil for Nausea and vomiting

CBD oil for Nausea anNausea and vomiting are linked to each other; you can not feel nauseous and have a vomit or expel the contents without being nauseated.

Both these feeling are different from each other. Nausea is defined as the feeling of discomfort related to the upper stomach in addition to an urge to expel contents or vomit.

Nausea is a debilitating condition where you have an urge to expel the contents of the stomach.

The phenomenon of nausea and vomiting involves the stimulation of the chemoreceptor zone which is responsible for identifying the emetic agents present in the blood.

The chemoreceptor zone has two specific receptors,i.e., Dopamine D2 along with Serotonin 5-HT3 receptors.

The use of CBD oil for relieving the feeling linked with nausea and vomiting occurs by interaction with the 5HT3A receptors leading to reduced binding of serotonin with these receptors and eventually less nausea and vomiting.

Multiple causes are leading to vomiting and nausea such as anxiety, stress, pain, digestive issues, head injuries, arteries associated with the lower brain region or matters linked with the middle or inner ear.

The centers which regulate the phenomenon of nausea and vomiting are connected with the lower part of the brain.

Medications such as chemotherapy also play a leading role in the induction of vomiting or nausea due to the stimulation of regulatory centers located in brain or irritation of the digestive system.

What are the treatment modalities for vomiting and nausea?

There are many medications available in the market which help in controlling the phenomenon of nausea and vomiting such as Bismuth Subsalicylate.

However, these drugs result in adverse effects which include constipation, darkened stools, ringing sounds and darker appearance of the tongue.

Other than these side effects, there are rare acute effects as well which include a headache, confusion, depression, anxiety, stomach pain, breathing issues, diarrhea, dizziness, profuse sweating, thirstiness, and slurred speech along with the vision problems.

To overcome these deleterious effects, the doctors and scientists have performed several studies to identify a natural compound which aids in controlling these two unusual phenomena,i.e., nausea and vomiting.

CBD oil has been revealed as a fantastic compound for reducing the effects of nausea and vomiting along with other numerous severe ailments without any severe side effects.


CBD OilCBD is one of the 113 cannabinoids present in the Cannabis plant.

The cannabinoids present in the Cannabis plant are the type of molecules which result in effects over the human body as well as animals.

THC, on the other hand, is a psychoactive agent also present in the CBD oil which has intoxicating effects.

CBD is termed as Cannabidiol which is a non-psychoactive agent and produces the intoxicating effects.

There is much research about these two most essential compounds present in the Cannabis plant due to high concentrations.

Beneficial medical effects of CBD oil on the human body

CBD Oil serves as a perfect curing agent for relieving nausea due to its medical properties i.e.

  • Aids in curing the vomiting and nausea linked with chemotherapy.
  • Serves as a perfect cure in conditions where pharmacological treatments become intolerable by the patients.
  • Serves in the reduction of nausea which might occur due to depression, anxiety or stress.
  • The CBD Oil aids in curing nausea due to extreme medical conditions.
  • It helps in treating motion sickness which if managed by pharmacologic agent leads to severe fatigue.
  • Serves as a perfect cure in conditions where the toxic response is expected to food such as gag reflex.

Other than these CBD oil aids in the following:

  • Suppresses the seizures
  • Aids in reducing the inflammatory disorders
  • Prevents an individual from neurodegenerative diseases by controlling the neurological activity and serving as an anti-oxidant agent.
  • The CBD oil cures the cancer-induced negative impact on the body by serving as an anti-cancer agent.
  • It aids in reducing the severity of anxiety and depression.
  • CBD oil has an amazing therapeutic effect which serves as an anti-emetic agent leading to the reduced vomiting and nausea abilities.

How can CBD oil help with nausea and vomiting?

The biological reason is present behind the progression of nausea and vomiting in an individual.

The phenomenon of nausea and vomiting is described as an act of defensive capability leading to the inhibition of consuming the toxic compounds by the human body.

Since there has been much research on the human body; it concluded that Endocannabinoid system present in the human body, comprises of the cannabinoid receptors which are involved in the regulation of vomiting and nausea.

The use of CBD oil results in the activation of a specific compound termed as 5-HT1A or 5-Hydroxytryptamine.

The CBD oil results in the stimulation of monoamine neurotransmitter leading to the reduced sensation of reflexes linked with nausea and vomiting.

The CBD oil has two essential compounds CBD and THC in fewer amounts. THC leads to the reduction of nausea and vomiting by the stimulation of CB1 receptors located in the brain.

These receptors aid in the regulation of nausea and vomiting phenomenon. The THC also stimulates the CB 1 receptors in the GIT tract leading to the reduction in intestinal motility. The CB1 receptors also aid in improving appetite.

The second essential component CBD aids in controlling the phenomenon of nausea by reducing the release of serotonin which leads to less vomiting and sensation of nausea.

The CB2 receptors are also activated by CBD which prevents you from feeling nausea and vomiting.

Due to this mechanism of action, CBD oil also aids in the reduction of vomiting and nausea which might occur due to pharmacological treatments or chemotherapy.

According to the studies, CBD oil is highly potent in treating these symptoms which might not be relieved with the use of medicines.

CBD supports in maintaining the high levels of anandamide leading to the inhibition of fatty acid enzymes which might result in degradation of this monoamine neurotransmitter.

It is assumed by the scientists that CBD provides the anti-nausea effects by prolonged stimulation of the CB1 receptors located in the brain.

Anandamide is an endogenous cannabinoid which stimulates the CB 1 receptors leading to anti-emetic effect.

The CBD oil is highly effective in curing the vomiting and nausea by the use of therapeutic doses. The CBD Oil interacts with the biological processes leading to the beneficial effects on the human body.

However, there needs to be further research and studies regarding the use of CBD oil for nausea and vomiting.

Avoid the use of medical cannabis in patients who have a mental illness, pregnant ladies or patients suffering from lungs, heart or immune system issues.

Animal and human studies which provide evidence that CBD oil works well in relieving nausea and vomiting

Animal and human studies which provide evidence that CBD oil works well in relieving nausea and vomitingAccording to an animal study, conducted with the use of CBDA or Cannabidiolic acid which helped in reduction of vomiting and nausea by stimulating the 5-HT1A receptors.

The study was conducted to look at the conditions in which nausea such as a toxin or motion sickness induced vomiting and nausea feelings.

The enhanced activation of 5-HT1A receptors leads to numerous beneficial medical effects associated with nausea. When the 5-HT1A receptors are blocked, it results in a delayed response of nausea in the animals during the study.

The study concluded that CBD serves as a potent and effective natural agent for inhibiting the reaction of nausea and vomiting in rats and shrews by the enhanced activation of 5-HT1A receptors. CBD oil shows promising results in treating vomiting and nausea along with anticipatory nausea.

According to the human study, conducted by British Pharmacological Society, it was evident that Endocannabinoid system aids in regulating vomiting and nausea in animals as well as humans.

The cannabinoids are useful as an anti-emetic agent which assists in controlling the symptoms associated with vomiting and nausea.

The CBD oil has promising results for treating chemotherapy-induced nausea and vomiting, especially for cancer patients.

According to the studies, CBD activates 5-HT1A receptors which result in anti-nausea and anti-emetic effects.

According to different studies conducted by Parker, Laimbeer, and Rock in 2011 and 1999, CBD content present in the Cannabis plant is highly effective in treating the symptoms associated with nausea and prevents anticipatory nausea which occurs in the chemotherapy patients.

It also concluded that THC is highly effective in reducing the chemotherapy-induced vomiting and nausea.

What is the best way to ingest cannabis for relieving nausea and vomiting?

Nausea patients want an instant relief, so they mostly prefer vaping or smoking rather than ingesting capsules, edibles, and CBD oil.

The oral consumption of Cannabis results in delayed effects,i.e., around 45 minutes to 1 hour.

Vaping is considered as a perfect option for those who do not find smoking comfortable and want an instant relief from nauseated feeling.

People who work at social places and suffer from nausea and vomiting, usually consider using CBD oil or tinctures which effects rapidly.

Which cannabis strains are finest for curing nausea?

Which cannabis strains are finest for curing nauseaCertain Cannabis strains are highly effective at combatting the debilitating feeling associated with vomiting and nausea.

The anecdotal reports conclude that South African Landrace Sativa Strain termed as Durban Poison works best for alleviating the nauseated feeling.

Other Cannabis strains which are best for reducing nausea include Trinity and Sour diesel.
The Indica cannabis strains which help in eliminating nausea are:

  • Sensi Star, Mango, Purple OG Kush and Mk Ultra.

The Hybrid Cannabis species for relieving nausea include:

  • Jillybean, Dutch Treat, Thin Mint Girl Scout cookies, White Fire OG, Deadhead OG, SFV OG.

Other than these there are two medical CBD therapies which aid in controlling chemotherapy-induced nausea and vomiting,i.e., Dronabinol and Nabilone.

Dosage guidelines for the consumption fo CBD oil

CBD oil is mostly taken in the form of drops or tincture orally by placing it underneath the tongue. The general dosage guidelines include the following:

  1. It is advised to consume 2.5-15 mg of CBD orally
  2. For the treatment of chronic pain consume 2.5-20 mg of CBD orally
  3. For sleep disorders, it is recommended to drink 40-160 mg of CBD oil orally

However, the correct dosage for CBD oil varies from person to person so follow these three simple tips:

  1. Start with a small dose
  2. Consume the dosage according to your weight
  3. Take advise from your doctor or healthcare professional


Science is emerging day by day and leading to further research and evidence regarding the use of CDB oil for relieving nausea and vomiting.

However, it is evident that CBD oil for nausea and vomiting is safe and serves as a useful treatment agent for people which is due to motion sickness, chemotherapy, stress response or gag reflex.

You can explore the beneficial effects for those who are intolerable to the adverse effects of pharmaceutical medicines. Consult your doctor before you plan on using CBD oil for nausea and vomiting.

Jennifer Kurtz studied medicine at the New Jersey School of Medicine (Rutgers). She is passionate about developing her knowledge of Cannabis, Nootropics, Kratom, and nutritional supplements. In addition to attending medical webinars and conferences, she loves to write research-based articles for magazines, healthcare professionals, and medical agencies.