Around 12% of the world’s population is affected by severe migraines or headaches as it is the most common source of pain. Migraines usually involve symptoms like nausea, over-sensitivity to light, coordination problems, disorientation, and vision problems.

Severe headaches are exhausting to endure and lasts long from 5 to 72 hours. By this time, the treatment of headaches and migraines have been painkillers including, Triptans, paracetamol, or ibuprofen.

Although painkillers help in alleviating the symptoms of migraines by blocking the pain pathways and constricting the blood vessels, due to their side effects people want some other ways of getting rid of severe migraines. This reason is where CBD oil makes its way to the top of the list.

Although research on CBD oil is insufficient, recent studies portrayed that migraines may occur due to the deficiency of endocannabinoids and odd inflammatory response.

The treatment of headaches by CBD oil has been mentioned in ancient texts thousands of years ago.

Also, many laboratory studies proved that CBD oil could efficiently treat all acute and chronic migraines.

CBD oil has been showing some significant benefits for an extensive range of medical conditions most importantly migraines.

What is CBD?

what is cbd oilCBD stands for Cannabidiol compound originated from the cannabis plants. It is proved that it provides uncountable health benefits.

It has been revealed that cannabinoid is an anti-inflammatory, antipsychotic, antidepressant, anxiolytic, anti-tumoral, anti-oxidant, neuroprotectant, analgesic compound.

Marijuana possesses around 113 various cannabinoids. These chemical compounds interact through endocannabinoid system. The two most potent cannabinoids for our health are Cannabidiol (CBD) and tetrahydrocannabinol (THC).

While both THC and CBD are useful in treating migraines and headaches, products of CBD as compared to THC products are less controversial, and safer therapy for patients because they are non-psychoactive.

This difference appeals patients to use CBD who are looking for relief from seizures, anxiety, headaches, pain, and inflammation without any significant side-effects.

Also, patients using CBD oil reported less severity and frequency of their migraine headaches, better sleep, and less nausea.

CBD efficiently decreases the number of migraine attacks by alleviating its most common triggers such as stress, sleep deprivation, and anxiety.

Furthermore, it showed promising results for various medical conditions including, diabetes, arthritis, multiple sclerosis, alcoholism, and much more.

What Is Migraine?

What Is MigraineEach year, around 47% of the population experience tension-type headache (38%), migraine (10%), and chronic daily headache (3%).

International Headache Society (IHS) define Migraine as a recurrent headache that falls into two categories a migraine with or without aura. It lasts from 4 to 72 hours with having different symptoms during an attack. These symptoms include sensitivity to light, vomiting, lack of energy, nausea, and throbbing headache.

CBD for Treating Migraines – How It Works?

Inside our body and brain, there are different cannabinoid receptors (CB1, CB2, WIN and anandamide receptor).

These Cannabinoid receptors consist of intra-and extracellular loops, and seven folded transmembrane helices that affect pain signals.

To activate the Cannabinoid receptors for modulating neural transmission, endocannabinoids, or endogenous cannabinoids play a vital role.

These different endocannabinoids are present in lesser amounts in the tissues and brain and actively participate to regulate various cerebral functions such as mood, pain, perception, appetite, and memory.

The dysfunction or lower level of endocannabinoids leads to migraine headaches. The deficiency of endocannabinoids can be addressed by introducing the cannabinoids in the body.

The neurologist and medical scientist “Dr. Ethan Russo” in an interview to the projected.or signals the role of CBD in bringing balance to endocannabinoid system.

CBD inhibits the uptake and enzymatic degradation of anandamide via FAAH and regulates many metabolic pathways, elevating anandamide extracellular concentrations.

By maintaining the higher level of anandamide in the body would potentially reduce the feelings of the pain.

Cannabinoids usually bind to the periaqueductal gray matter that modulates pain transmission. The area of the brain associated with severe headaches consists of higher levels of the endocannabinoid receptor CB1.

Also, CBD helps in preventing the metabolism of anandamide that ultimately reduces the regulation of pain. Being an anti-inflammatory compound, it reduces pain in the body and diminishes other immune-system responses.

However, more research is required to understand how CBD binds on an allosteric site receptor to alter the endogenous cannabinoids.

Important Facts to Know About CBD Oil for Migraines

  • CBD in oil form can either get extracted from hemp or marijuana. CBD products possess a very minute amount of THC that give rise to the feelings of getting stoned or high. Also, CBD oil is non-psychoactive, and studies revealed that CBD oil could counteract the paranoia or anxiety caused by THC.
  • The deficiency of endocannabinoids causes an imbalance in the homeostasis of the body that ultimately results in the development of the migraines. When a migraine begins in response to any trigger such as smell, hunger, bright light or hormones CBD oil helps in stimulating the production of endocannabinoids that results in maintaining the body’s homeostasis.
  • CBD oil extracted from marijuana consists of THC. Cannabinoids containing THC levels are outlawed in the US. Therefore, CBD oil is only legal if it is extracted from hemp.
  • Serotonin is an essential chemical neurotransmitter that helps in regulating mood, appetite, memory, social behavior, sleep, and much more. Serotonin has profound effects in causing depression and migraines. However, CBD oil helps in diminishing the intensity and frequency of the Serotonin levels in the central nervous system and eliminating the risks of the migraine attacks.
  • CBD oil is available in various forms including, vape oils, capsules, and drops. Patients using CBD oils showed improvement in their rate of migraine attacks. Reported by the community members, CBD oil available in drops is the most popular form for personal use.

CBD and Migraines: What Research Says?

cbd and migrainesUnfortunately, the research on CBD oil is insufficient due to the obstacles related to the legalization of the cannabis.

However, some studies proved that CBD oil might help in all forms of acute and chronic migraines.

A that is a medical cannabis industry company based in California. They surveyed around 2495 patients over a six-month period from March 2015 to August 2015 who used medical marijuana.

The purpose was to find out the impact of CBD on migraine patients. Only 621 patients were included in the survey that met the criteria.

The result of this study showed that 100 percent of the migraine patients noticed a reduction in their discomfort and pain. This CBD oil proved to be effective in treating migraine attacks and its intensity.

Also, two medical marijuana specialty clinics conducted a study in Colorado and published it in May 2016, in the Pharmacotherapy Journal showing the findings that 121 migraine patients used medical marijuana for treating their headaches from the year 2010 to 2014 and found their migraine frequency dropped to 4.6 from 10.4.

They used various forms of CBD oil in this span and found that inhaling form helped them in aborting the headache at the start. Also, they reported that edible forms of CBD oil caused many adverse side-effects.

Many evidence proved that implication of CBD oil is even safe at higher doses because some patients tried and tested it and reported relief from severe migraine attacks.

Many institutes nowadays are working on finding CBD oil preventing or treating value in cancer.

While the clinical studies for CBD oil are inadequate enough anecdotal evidence obtained from surveys exists that proves it has profound effects on migraine headaches.

CBD Oil Dose for Migraines

Cannabis is used for various health reasons including inflammation, neurological symptoms, and migraine headaches.

Due to the availability of CBD oil in various forms and concentrations including, spray, tablets, vaporizers, sublingual drops and edible as in gum or candy, multiple physicians still feel resistant to prescribe CBD oil because usually, they are not sure about prescribing the dosage.

Also, the thing to keep in mind is that everyone is different and reacts differently to the CBD oil dosage, therefore, it is ideal, to begin with, the smaller dosage, and increasing it gradually until you feel the result you desire. This technique will permit your body to get used to CBD oil and diminish the risk of any side-effects.

Start with the lowest dosage of 2 drops to be safe. Taking a dose of CBD oil twice a day, I.e. morning and evening is sufficient.

Also, if you feel trouble sleeping, you can take another dose before relaxing if you do not take sleep aid such as CBN.

The recommended treatment for the CBD tincture is 5 to 10 drops, three times a day depending on the symptoms, relief, and side-effects.

Also, it is recommended to increase the dose by 25mg every three to four weeks until the symptoms relief and to reduce this dosage with any worsening symptoms.

In order to treat chronic pain 2.5 to 20 mg of CBD oil should be taken by mouth for around 25 days.

How to Apply CBD Oil for Migraines?

CBD oil for migraines is available in multiple forms. Most effective forms are ingestion or vaping. One of the most effective and simplest ways of using it is the sublingual method.

The sublingual method requires placing a few drops of CBD oil beneath your tongue, and then it diffuses through the thin membrane and moves to the place where it is needed and shows beneficial effects.

This oral CBD is the best method for the beginners who want to get rid of their migraine attacks.

Also, it causes almost no side-effects. You can even eat a CBD infused treat or tablets of CBD oil. If you are at home and you don’t have to go anywhere, and you are suffering from a severe migraine, then you can use the vaping method of CBD oil.

The CBD oil vaping method can be very useful in treating migraines because NCI reported that the inhaling process or vaping transport the compounds directly into the bloodstream much rapidly than any other method.

There are many methods available that can benefit you, therefore, do your research when purchasing any CBD oil product online.

Risks for Using CBD for Treating Migraines

Every person reacts differently to the dosage of CBD oil and to its side-effects too. You can easily avoid getting high and side-effects by decreasing the dosage gradually.

CBD oil can cause an increase in appetite, euphoria, and change in perception in migraine patients.

Also, the short-term side-effects include impaired motor skills, dry mouth, anxiety, short-term memory, the feeling of paranoia, and red eyes. If you start feeling high, it’s best to sleep or take a nap in order to pass the feeling.

Overall the side-effects caused by the CBD oil are all minimal; therefore, migraine patients are considering this oil for relieving pain instead of those addictive pain medications.

Although, gastric problems, drowsiness, fatigue, and dizziness are the most common type of side-effects of the CBD oils.

Side-effects also vary depending on the form and quality of CBD oil used for example if you use the vaping form it will cause you lung irritation that can ultimately lead to breathing difficulties, wheezing, and chronic cough.

Also, if you have asthma or any respiratory disease, your doctor will initially inform you to avoid the vaping form.

If any of the side-effects occur, it depends on your quality of the CBD oils. It is impossible to overdose this CBD oil; furthermore, it is described that even overdoses of CBD oil are not harmful or disadvantageous for our health.

In hundreds of decades, there is not even a single death recorded in the history caused by the use of cannabis or CBD oil, therefore, it is a perfect idea to use CBD oil for migraines because it produces almost no side-effects.

Best CBD Oil for Migraines

Some of the patients reported that they are getting headaches as a side-effect by using the CBD oil.

However, later it was discovered that the product they were using was of low quality and the ingredients incorporated in that CBD oil was various kinds of alcohol such as ethanol, harsh chemicals, and few preservatives.

Therefore, one of the most important thing to keep in mind while purchasing a CBD oil is to buy the best quality available in the market.

You can buy it from CBDfx as they claim their CBD oil product to be organic, family-farmed Colorado grew cannabis.

You can also purchase CBDPure Hemp Oil that claims to maximize your well-being and health. It is organic and has a natural hemp flavor. It is usually available with money back guarantee backed by 90 days.

Original CBD oil is also available by Elixinol that is of high potency and combined with terpenes, and it is cost-effective.

There are multiple brands from where you can easily purchase the CBD oil such as Beyond Botanicals, CBD hemp oil from CBDfx, and from

Jennifer Kurtz studied medicine at the New Jersey School of Medicine (Rutgers). She is passionate about developing her knowledge of Cannabis, Nootropics, Kratom, and nutritional supplements. In addition to attending medical webinars and conferences, she loves to write research-based articles for magazines, healthcare professionals, and medical agencies.