Are you suffering from pain? Is it acute or chronic nature? Do you feel fatigued? Is it hard for you to manage activities that you once did easily? Have you been taking medications for it? Are they effective? Are you looking for new solutions?
If yes, this article is for you. This article offers you knowledge about two new herbs that are known for their pain relieving property as well as stimulant action. Yes, we are talking about Kratom and Akuamma Seeds. Akuamma and Kratom together for pain and energy are the new herbs used by many people throughout the world.
Kratom or Mitragyna Speciosa is a stimulant and a painkiller that mainly used for Opiate withdrawal, and it has grown in regions of Southeast Asia.
Akuamma plant, also known as Picralima Nitida has adrenergic antagonist alkaloids like akuammine and pricing. These alkaloids are responsible for analgesia, euphoria, and stimulation at moderate doses. It grew in Tropical areas of Africa like Ivory, Ghana, Cameroon, Nigeria, and Uganda, etc. The dry seeds of this flower used as a medicine for malaria, diabetes, pain and opiate withdrawal.
Mechanism of action of Kratom and Akuamma
The active alkaloid of Kratom; mitragynine acts as an agonist at the opioid receptors present in the brain. It acts on the mu, delta and kappa receptors, like that of Opiates. That prompts direct stimulation and euphoria. Also, these receptors are involved in the analgesic pathway of the human body.
Through signal transduction, the alkaloids of Kratom send a message to the neuronal cell, and they act by increasing the output of enkephalins and endorphins. These two neurotransmitters are part of the analgesia pathway. They work by crushing pain signals at various points in the pain pathway situated in the anterolateral spinothalamic pathway.
Akuamma seeds have alkaloids known as akuammine and pricing. Akuammine and another alkaloid akuammigine bind to the mu-opioid receptors and act as agonists. These alkaloids are responsible for pain killing as well as stimulating effects.
So basically both Kratom and Akuamma have alkaloids that act on the opioid receptors to cause analgesia and increase energy levels. That is why these two herbs used in different parts of the world for chronic debilitating pain as well as fatigue.
Kratom and Akuamma for pain
Very few people know that other than opiates there are drugs and natural herbs that can be used to get rid of chronic pain and discomfort. These alternatives, if well-researched can cause a significant discovery in Pharmacology leading one to safer alternative treatments for chronic pain.
Kratom and Akuamma are two of the natural herbs that have used for centuries for pain; however, due to lack of research, the FDA doesn’t approve them, though it’s a well-known fact that as compared to opiates these herbs have fewer or almost negligible side effects.
Since both the herbs act on the Pain pathway receptors, both of them are highly beneficial for treating pain. The alkaloid percent in Akuamma seeds binds to the opioid receptors with six times as much potency as that of Codeine.
That signifies that it can be even more effective than opiates. Akuammine, on the other hand, binds very strongly to the kappa opioid receptors helping in suppressing pain.
Kratom has used in the treatment of arthritis, pain due to tumors and cancer, osteoporosis, trauma, fractures, postoperatively and in various other chronic painful conditions.
Kratom and Akuamma for energy
Kratom has been used recreationally for years to enhance energy levels. With the advent of Akuamma, the popularity of Kratom has challenged as Akuamma is also known for boosting energy levels, making one more efficient, enhancing cognition and improving confidence level and communication skills.
Though this property of Akuamma and Kratom can be used to increase socialization, it has used by patients who suffer from chronic fatigue and lethargy. It has also been used by night shift workers to stay awake and perform their duties efficiently.
The level of energy is inversely proportional to the dose of Akuamma and Kratom. The less you take, the more you feel energetic; by less, we mean an optimum dose. At higher doses, one usually feels dizzy and as the sedative property of these herbs is enhanced at higher doses.
Dosage of Kratom and Akuamma for pain and energy
Various types of Kratom have different prescriptions for pain and energy. And, generally considering the built, physique and health of every individual, it can be rightly said that there is no appropriate dose of pain and energy.
The treatment also depends on the facts that have you taken the herbs previously or not or do you bring them on a daily basis or not. For a chronic user, a large dose of Akuamma and Kratom needs to taken for relieving pain and boosting energy levels. For a newbie, the treatment considerably reduced.
- Dose of Kratom: Red Bali: 2-6 grams
- Maeng Da: 1 gram to 5 grams (Red Maeng Da)
- White Maeng Da: 3-7 grams (Doses higher than 7 grams cause intense sedation)
Bali, Indo and Borneo Kratom shouldn’t be used for energy as they boost energy levels very less. The green and white vein strains of Kratom aren’t effective painkillers so they should avoid.
The dose of Akuamma seeds: According to reliable sources, the daily dosage for pain could be everywhere among 250mg to 500mg. That dose equals to consumption of 1-2 seeds.
For severe pain, the dose is increased to 2 -4 grams, and in some cases, it can even reach 6 grams. The consequences last for an average time of 4-5 hours.
For best results, always ensure that you start using a drug or supplement at small doses and gradually increase it to find your sweet spot.
Adverse effects of Kratom and Akuamma
The main side effects of Akuamma include a headache, nausea and GI distress, and this occurs in users who consume more than 10 grams of Akuamma. On the other hand, Kratom causes sedation at higher doses and may cause nausea and vomiting at mild doses due to its bitter taste.